| Bioactivity | CYP1B1-IN-5 (Compound 6q) is a potent and selective cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 4.7 nM[1]. |
| Invitro | CYP1B1-IN-5 (Compound 6q) 通过与残基 Phe231、Phe134 和血红素形成 π-π 叠加相互作用，与 CYP1B1 的结合口袋结合[1]。 |
| Name | CYP1B1-IN-5 |
| CAS | 176442-56-1 |
| Formula | C14H8INO2 |
| Molar Mass | 349.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yi L, et al. A new class of CYP1B1 inhibitors derived from bentranil. Bioorg Med Chem Lett. 2022 Dec 21;80:129112. |