Bioactivity | CXF-009 is a selective and covalent FGFR4 inhibitor, with the IC50 of 48 nM. CXF-009 targeting Cys477 and Cys552 of FGFR4, and can be used for the study of hepatocellular carcinoma[1]. |
CAS | 2727084-00-4 |
Formula | C33H38N8O5 |
Molar Mass | 626.71 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chen X, et al. Structure-based design of a dual-warhead covalent inhibitor of FGFR4. Commun Chem. 2022;5(1):36. Published 2022 Mar 17. |