| Bioactivity | AC-263093 (AC-093) functionally activates NPFFR2 and blocks activation of NPFFR1 with pKis of 6.9 and 7.0, respectively. AC-263093 has the potential for reversing opiate tolerance research[1]. . | ||||||||||||
| In Vivo | AC-263093 (10 mg/kg；腹腔注射) 完全逆转大鼠对硫酸吗啡的耐受性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: | ||||||||||||
| CAS | 849459-86-5 | ||||||||||||
| Formula | C8H8Br2N4 | ||||||||||||
| Molar Mass | 319.98 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. David H Malin, et al. Reversal of morphine tolerance by a compound with NPFF receptor subtype-selective actions. Neurosci Lett. 2015 Jan 1:584:141-5. |