| Bioactivity | CTL26 is a potent and orally active α-glucosidase inhibitor with an IC50 value of 2.81 µM. CTL26 shows anti-diabetic efficacy[1]. |
| Target | IC50: 2.81 µM (α-glucosidase) |
| In Vivo | CTL26 (25, 50 mg/kg; p.o.; daily for 4 weeks) 在链脲佐菌素 (HY-13753) 诱发的糖尿病小鼠中显示出抗糖尿病功效[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| Formula | C25H18N6O3S |
| Molar Mass | 482.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liang B, et al. Novel thiosemicarbazide-based β-carboline derivatives as α-glucosidase inhibitors: Synthesis and biological evaluation. Eur J Med Chem. 2024 Jun 12;275:116595. |