ARF(26–44), cell-permeable_product_DataBase

Bioactivity	ARF(26–44), cell-permeable is a cell-penetrating peptide derived from a specific amino acid sequence of the p14ARF tumor suppressor protein. As a functional inhibitor of FoxM1, ARF(26–44) cell-permeable shows significant anti-tumor activity in the treatment of mouse hepatocellular carcinoma (HCC), significantly increasing tumor cell apoptosis and reducing tumor cell proliferation and angiogenesis. ARF(26–44), cell-permeable can be used in research on tumor therapy[1].
CAS	935732-44-8
Sequence	{d-(Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg)}-Lys-Phe-Val-Arg-Ser-Arg-Arg-Pro-Arg-Thr-Ala-Ser-Cys-Ala-Leu-Ala-Phe-Val-Asn
Shortening	{d-(Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg)}-KFVRSRRPRTASCALAFVN
Formula	C149H267N69O33S
Molar Mass	3585.22
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Gusarova G A, et al. A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment[J]. The Journal of clinical investigation, 2007, 117(1): 99-111.

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