| Bioactivity | CTB is a potent p300 histone acetyltransferase activator[1]. CTB can effectively induce apoptosis in MCF-7 cells[2]. |
| Invitro | CTB (10, 50, 100, 150, 200, and 250 µM; 10 min) enhances p300 HAT activity of p300 in a dosedependent manner[1].CTB (0-200 μM; 24 hours) inhibits the viability of MCF-7 cells with an IC50 of 85.43 μM[2].CTB (85.43 μM; 24, 48 and 72 h) induces time dependence apoptosis of MCF-7 cells[2].CTB (50 uM; 24 h) increases p300/CBP activity , and reduces autophagic flux in primary neurons[3]. Cell Viability Assay[2] Cell Line: |
| Name | CTB |
| CAS | 451491-47-7 |
| Formula | C16H13ClF3NO2 |
| Molar Mass | 343.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |