Bioactivity | CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress[1]. |
Invitro | CP26 exhibits a significant inhibitory activity against both DENV and ZIKV, providing substantial protection to the host cells against virus-induced cell death[1].CP26 inhibits the ubiquitination and degradation of misfolded ER proteins[1]. |
Name | CP26 |
CAS | 500285-30-3 |
Formula | C13H8Cl4 |
Molar Mass | 306.01 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jingjing Ruan, et al. A small molecule inhibitor of ER-to-cytosol protein dislocation exhibits anti-dengue and anti-Zika virus activity. Sci Rep. 2019 Jul 29;9(1):10901. |