PeptideDB

CP26

CAS: 500285-30-3 F: C13H8Cl4 W: 306.01

CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 comple
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Bioactivity CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress[1].
Invitro CP26 exhibits a significant inhibitory activity against both DENV and ZIKV, providing substantial protection to the host cells against virus-induced cell death[1].CP26 inhibits the ubiquitination and degradation of misfolded ER proteins[1].
Name CP26
CAS 500285-30-3
Formula C13H8Cl4
Molar Mass 306.01
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Jingjing Ruan, et al. A small molecule inhibitor of ER-to-cytosol protein dislocation exhibits anti-dengue and anti-Zika virus activity. Sci Rep. 2019 Jul 29;9(1):10901.