| Bioactivity | CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulation. CP-91149 has the potential for Type II (insulin-dependent) diabetes study[1]. | ||||||||||||
| Invitro | CP-91149 treatment decreases muscle GP activity by converting the phosphorylated AMP-independent α form into the dephosphorylated AMP-dependent b form and inhibiting GP α activity and AMP-mediated GP b activation[1].CP-91149 (10, 30, 50 μM) inhibits brain GP and causes glycogen accumulation in A549 cells[2]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | CP-91149 | ||||||||||||
| CAS | 186392-40-5 | ||||||||||||
| Formula | C21H22ClN3O3 | ||||||||||||
| Molar Mass | 399.87 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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CP-91149
CAS: 186392-40-5 F: C21H22ClN3O3 W: 399.87
CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulatio
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