| Bioactivity | TFMB-(R)-2-HG, a cell membrane-permeable version of (R)-2-HG, is a carcinogenic factor in Acute myeloid leukemia (AML).TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cells differentiation in response to estrogen withdrawal[1]. | |||||||||
| Target | Carcinogenic factor | |||||||||
| Name | TFMB-(R)-2-HG | |||||||||
| CAS | 1445700-01-5 | |||||||||
| Formula | C13H11F3O4 | |||||||||
| Molar Mass | 288.22 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013 Mar 29;339(6127):1621-5. |
TFMB-(R)-2-HG
CAS: 1445700-01-5 F: C13H11F3O4 W: 288.22
TFMB-(R)-2-HG, a cell membrane-permeable version of (R)-2-HG, is a carcinogenic factor in Acute myeloid leukemia (AML).T
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