CP-135807_product_DataBase

Bioactivity	CP-135807 is an orally active and selective 5-HT1D agonist (IC50=3.1 nM), bovine). CP-135807 mediates central psychoactivity and can be used in antidepressant research[1][2].
In Vivo	鸽子被训练在一个固定比例的食物提供下啄一个键。CP-135807 (0.1 mg/kg; 肌肉注射; 单剂量) 则能够完全和剂量依赖地替代成年雄性卡诺鸽子的训练剂量[1]。
Name	CP-135807
CAS	151272-90-1
Formula	C19H21N5O2
Molar Mass	351.40
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Mansbach RS, et al. CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology (Berl). 1996 Dec;128(3):313-9. [2]. Macor J E, et al. Use of 2, 5-Dimethylpyrrole as an Amino-Protecting Group in an Efficient Synthesis of 5-Amino-3-[(N-methyl-pyrrolidin-2 (R)-yl) methyl] indole[J]. The Journal of Organic Chemistry, 1994, 59(24): 7496-7498.

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