| Bioactivity | COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity[1]. |
| In Vivo | COX-1/2-IN-3 (Compound 7a) (1.25 and 0.625 mg/ear) exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity[1]. |
| Name | COX-1/2-IN-3 |
| CAS | 2428387-82-8 |
| Formula | C14H8N2O8 |
| Molar Mass | 332.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gonçalves DS, et al. Synthesis of novel 3,5,6-trisubstituted 2-pyridone derivatives and evaluation for their anti-inflammatory activity. Bioorg Med Chem. 2020 Jun 15;28(12):115549. |
COX-1/2-IN-3
CAS: 2428387-82-8 F: C14H8N2O8 W: 332.22
COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicit
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.