| Bioactivity | CMX-2043 is a novel analogue of α-Lipoic Acid (HY-N0492). CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model[1][2]. | ||||||
| Invitro | CMX-2043 (15-250 mM; 10 min) has great peroxyl radical absorbance capacity[1].CMX-2043 (1.5 μM) weakly inhibits spleen tyrosine kinase (Syk) and tunica interna endothelial cell kinase (Tie2)[1].CMX-2043 (50 μM; 45 min) activates Akt phosporylation via PI3K pathway in A549 cells[1].CMX-2043 (2.5 mM; 30 min) diminishes the rise in cytosolic calcium in a concentration-dependent manner in CHO-M1-WT3 cells[1]. Immunofluorescence[1] Cell Line: | ||||||
| Name | CMX-2043 | ||||||
| CAS | 910627-26-8 | ||||||
| Formula | C16H26N2O6S2 | ||||||
| Molar Mass | 406.52 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
CMX-2043
CAS: 910627-26-8 F: C16H26N2O6S2 W: 406.52
CMX-2043 is a novel analogue of α-Lipoic Acid (HY-N0492). CMX-2043 is effective in antioxidant effect, activation of in
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.