| Bioactivity | CL67 is a potent hypoxia-inducible factor (HIF) pathway inhibitor. CL67 interferes G-quadruplex structures within promoter sequences. CL67 can be used in research of renal cancer[1]. |
| Invitro | CL67 (RCC4 和 RCC4VHL 细胞) 以剂量依赖性方式抑制 HIF-1α 蛋白[1]。 |
| Name | CL67 |
| CAS | 1401242-86-1 |
| Formula | C38H42N10O2 |
| Molar Mass | 670.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sarah JW, et, al. CL67: A novel G-quadruplex stabilising agent inhibits the HIF-1 pathway. Cancer Res (2011) 71 (8_Supplement):4506. |