| Bioactivity | CK0106023 is a potent and specific allosteric inhibitor of KSP with a Ki value of 12 nM, showing antitumor activity. CK0106023 causes mitotic arrest and growth inhibition in several tumor cell lines. CK0106023 exhibits antitumor activity in tumor-bearing mice[1][2]. |
| CAS | 336115-72-1 |
| Formula | C30H32BrClN4O2 |
| Molar Mass | 595.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. You-Ling Fan. End-capped polyarylene polyethers, articles made therefrom and process for preparing such polyarylene polyethers. EP0106023B1. 1988 March 30. [2]. Sakowicz R, et al. Antitumor activity of a kinesin inhibitor. Cancer Res. 2004 May 1;64(9):3276-80. |
CK0106023
CAS: 336115-72-1 F: C30H32BrClN4O2 W: 595.96
CK0106023 is a potent and specific allosteric inhibitor of KSP with a Ki value of 12 nM, showing antitumor activity. CK0
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