| Bioactivity | CGP52608 is a selective agonist for the RZR/ROR receptor, known for its anti-tumor activity, and has almost no affinity for the cell surface G-protein coupled melatonin receptor. CGP52608 can inhibit the growth of mouse 16/C breast cancer cells. CGP52608 can induce the formation of vesicles in diatoms[1][2]. |
| CAS | 87958-67-6 |
| Formula | C8H12N4OS2 |
| Molar Mass | 244.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. S T Tslm, et al. CGP 52608-induced cyst formation in dinoflagellates: possible involvement of a nuclear receptor for melatonin. J Pineal Res. 1996 Sep;21(2):101-7. [2]. Katarzyna Winczyk, et al. Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells. Neuro Endocrinol Lett. 2006 Jun;27(3):351-4. |