| Bioactivity | CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1]. |
| Invitro | CFTR corrector 6 (Example 27) has EC50s of 1.25 nM and 1.27 nM for primary cystic fibrosis human bronchial epithelial (CF hBE) cells and fischer rat thyroid (FRT) cell lines[1]. |
| Name | CFTR corrector 6 |
| CAS | 2226970-01-8 |
| Formula | C22H13F4N9 |
| Molar Mass | 479.39 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Joseph Walter Strohbach, et al. Pyrrolopyrimidines as cftr potentiators. WO2018094137A1 |
CFTR corrector 6
CAS: 2226970-01-8 F: C22H13F4N9 W: 479.39
CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.