| Bioactivity | CDK4/6-IN-17 (compound 12) is an orally active CDK4/6 inhibitor with IC50 ranging of 10-100 nM in BE(2) cells. CDK4/6-IN-17 inhibits tumor growth in COLO205 xenograft model[1]. |
| Target | CDK4/6 |
| Name | CDK4/6-IN-17 |
| CAS | 2035069-96-4 |
| Formula | C27H28F4N8 |
| Molar Mass | 540.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao X, et al. Preparation of benzopyrroloimidazolyl compounds as CDK4/6 kinase inhibitors. World Intellectual Property Organization, WO2016173505 A1. 2016-11-03. |
CDK4/6-IN-17
CAS: 2035069-96-4 F: C27H28F4N8 W: 540.56
CDK4/6-IN-17 (compound 12) is an orally active CDK4/6 inhibitor with IC50 ranging of 10-100 nM in BE(2) cells. CDK4/6-IN
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