Bioactivity | CDK2 degrader 5 (compound 12) is a degrader for CDK2, with the Dmax of >50% and ≤80% in HiBiT Assay. CDK2 degrader 5 plays an important role in cancer research[1]. |
CAS | 2923574-11-0 |
Formula | C29H27N3O5 |
Molar Mass | 497.54 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Monte Rosa Therapeutics, Inc. Preparation of 3-(6-substituted-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives that mediate the degradation of cyclin-dependent kinase (CDK2) and are useful in the treatment of various disorders, such as cancer. World Intellectual Property Organization, WO2023069700 A1 2023-04-27 |