| Bioactivity | CDK2 degrader 1 (Compound 3) is an orally active cyclin-dependent kinase 2 (CDK2) degrader based on PROTAC technology. CDK2 degrader 1 binds to cereblon to induce ubiquitination and subsequent proteasomal degradation of the CDK2. CDK2 degrader 1 is used in the research of a wide range of cancers (Red: spiro[3.3]heptan-2- ylmethyl carbonochloridate; Blue: N,N-diisopropylethylamine; Black: linker)[1]. |
| CAS | 3036604-59-5 |
| Formula | C23H27F2N3O4 |
| Molar Mass | 447.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fasching B, et al. Compounds that mediate protein degradation and methods of use thereof[J]. US patent WO2023069700A1, 2022. |
CDK2 degrader 1
CAS: 3036604-59-5 F: C23H27F2N3O4 W: 447.47
CDK2 degrader 1 (Compound 3) is an orally active cyclin-dependent kinase 2 (CDK2) degrader based on PROTAC technology. C
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This product is for research use only, not for human use. We do not sell to patients.