| Bioactivity | CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM. | ||||||||||||
| Name | CD80-IN-3 | ||||||||||||
| CAS | 486449-65-4 | ||||||||||||
| Formula | C17H10FN3O3 | ||||||||||||
| Molar Mass | 323.28 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Huxley P, et al. High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy. Chem Biol. 2004 Dec;11(12):1651-8. |