| Bioactivity | CD 10899 is a hydroxylated metabolite of Volasertib (HY-12137). CD 10899 is pharmacologically active against Polo-like kinase 1 (PLK1) (IC50: 6 nM). Volasertib is an orally active, highly potent and ATP-competitive PLK1 inhibitor. CD 10899 can be used for research of cancer[1]. |
| CAS | 1331770-20-7 |
| Formula | C34H50N8O4 |
| Molar Mass | 634.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lang I, et al. Potential Drug-Drug Interactions with Combination Volasertib + Itraconazole: A Phase I, Fixed-sequence Study in Patients with Solid Tumors. Clin Ther. 2020 Nov;42(11):2214-2224. |
CD 10899
CAS: 1331770-20-7 F: C34H50N8O4 W: 634.81
CD 10899 is a hydroxylated metabolite of Volasertib (HY-12137). CD 10899is pharmacologically active against Polo-like ki
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