| Bioactivity | CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling[1]. |
| Target | IC50: VEGFR |
| Name | CBO-P11 |
| CAS | 612096-46-5 |
| Sequence | Cyclo(Asp-Phe-Pro-Gln-Ile-Met-Arg-Ile-Lys-Pro-His-Gln-Gly-Gln-His-Ile-Gly-Glu) |
| Shortening | Cyclo(RIKPHQGQHIGEDFPQIM) |
| Formula | C94H145N29O25S |
| Molar Mass | 2113.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Stéphanie Deshayes, et al. "Click" conjugation of peptide on the surface of polymeric nanoparticles for targeting tumor angiogenesis. Pharm Res. 2011 Jul;28(7):1631-42. |
CBO-P11
CAS: 612096-46-5 F: C94H145N29O25S W: 2113.40
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is mod
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