| Bioactivity | CALP1 TFA is a calmodulin (CaM) agonist (Kd of 88 µM) with binding to the CaM EF-hand/Ca2+-binding site. CALP1 TFA blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition of calcium channel opening. CALP1 TFA blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 TFA activates CaM-dependent phosphodiesterase activity[1][2][3][4]. | ||||||
| Name | CALP1 TFA | ||||||
| Sequence | Val-Ala-Ile-Thr-Val-Leu-Val-Lys | ||||||
| Shortening | VAITVLVK | ||||||
| Formula | C42H76F3N9O12 | ||||||
| Molar Mass | 956.10 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |