| Bioactivity | C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxNI209F was not significant.[1]. | ||||||||||||
| Target | LuxN/AI-1 | ||||||||||||
| CAS | 1036730-46-7 | ||||||||||||
| Formula | C23H28ClN3O4S | ||||||||||||
| Molar Mass | 478.00 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Swem LR, et al. Deducing receptor signaling parameters from in vivo analysis: LuxN/AI-1 quorum sensing in Vibrio harveyi. Cell. 2008 Aug 8;134(3):461-73. |
C450-0730
CAS: 1036730-46-7 F: C23H28ClN3O4S W: 478.00
C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane
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