Bioactivity | Bucumolol hydrochloride is a β-adrenergic receptor antagonist that can slow heart rate (negative chronotropic effect) and reduce cardiac contractility (negative inotropic effect). Bucumolol hydrochloride has antiarrhythmic and local anesthetic activity and can be used in the study of cardiovascular diseases[1]. |
CAS | 36556-75-9 |
Formula | C17H24ClNO4 |
Molar Mass | 341.83 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Nakayama, Koichi, et al. Antiarrhythmic activity of dextro-and levo-isomers OF 5-methyl-8-(2-hydroxy-3-t-butylamino-propoxy) coumarin hydrochloride (bucumolol), a β-adrenergic blocking agent, on aconitine-induced atrial and ouabain-induced ventricular arrhythmias in dogs. The Japanese Journal of Pharmacology 29.6 (1979): 935-945. |