Bioactivity | BuChE-IN-12 is a selective BuChE inhibitor (IC50=0.52 µM) that acts via affecting CAS and PAS sites and has potential effects against oxidative stress. BuChE-IN-12 can be used in the study of Alzheimer's disease[1]. |
CAS | 1363947-94-7 |
Formula | C22H20N4 |
Molar Mass | 340.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sadeghian, et al. Synthesis, biological evaluation, molecular docking, and MD simulation of novel 2, 4-disubstituted quinazoline derivatives as selective butyrylcholinesterase inhibitors and antioxidant agents. Scientific Reports 14.1 (2024): 15577. |