| Bioactivity | Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases[1][2]. |
| Target | Caspase 8. |
| Name | Boc-AEVD-CHO |
| CAS | 220094-15-5 |
| Sequence | Boc-Ala-Glu-Val-Asp-CHO |
| Shortening | Boc-AEVD-CHO |
| Formula | C22H36N4O10 |
| Molar Mass | 516.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Garcia-Calvo M, et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13. [2]. Grassmé H, et al. Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene. 2003 Aug 21;22(35):5457-70. |