| Bioactivity | Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Compound 24, Cys modified with M6Pn) is a mannose-6-phosphate (M6Pn)-peptide conjugate capable of binding to targeted ligands of various proteins and successfully internalizing and degrading them through M6PR. Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 can be utilized in the research of lysosomal targeting chimeras (LYTACs) based on M6Pn[1]. |
| Formula | C124H230N20O63P6S7 |
| Molar Mass | 3419.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Stevens CM, et al. Development of Oligomeric Mannose-6-phosphonate Conjugates for Targeted Protein Degradation. ACS Med Chem Lett. 2023;14(6):719-726. Published 2023 Mar 3. |
Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn)
CAS: F: C124H230N20O63P6S7 W: 3419.55
Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Compound 24, Cys modified with M6Pn) is a mannose-6-phosphate (M6Pn)-peptide conjug
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