| Bioactivity | Apoptotic agent-4 (Compound 9) is a apoptosis inducer. Apoptotic agent-4 inhibits VEGFR-2 with an IC50 of 0.5717 μM. Apoptotic agent-4 inhibits cancer cell proliferation and arrests the cell at both the G2/M and Pre-G1 phases[1]. |
| Invitro | Apoptotic agent-4 对 HCT-116、HepG-2、MCF-7 细胞具有抗增殖作用，IC50s 分别为 8.05、5.15、9.77 μM。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Apoptotic agent-4 相关抗体: |
| Formula | C22H28N4O3S2 |
| Molar Mass | 460.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Elgammal WE, et al. Design, synthesis, and anticancer evaluation of N-sulfonylpiperidines as potential VEGFR-2 inhibitors, apoptotic inducers. Bioorg Chem. 2024 Apr;145:107157. |