PeptideDB

Big Endothelin-1 (1-39), porcine

CAS: 120796-99-8 F: C193H289N49O58S5 W: 4384.10

Big Endothelin-1 (1-39), porcine is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide.
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Bioactivity Big Endothelin-1 (1-39), porcine is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide. Big Endothelin-1 (1-39), porcine has similar pressor effects in vivo[1].
Invitro Endothelin-1 (ET-1) is a potent, endothelial cell-derived, 21-amino acid peptide that has potent vasoconstricting properties and may participate in the regulation of blood pressure and regional blood flow[1].
In Vivo Big Endothelin-1 (1-39), porcine, the cDNA deduced putative precursor of ET-1, has been reported to have similar pressor effects in vivo[1].
Name Big Endothelin-1 (1-39), porcine
CAS 120796-99-8
Shortening CSCSSLMDKECVYFCHLDIIWVNTPEHIVPYGLGSPSRS (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)
Formula C193H289N49O58S5
Molar Mass 4384.10
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. A Hoffman, et al. Opposite effects of endothelin-1 and Big-endothelin-(1-39) on renal function in rats. Eur J Pharmacol. 1990 Jul 17;182(3):603-6.