| Bioactivity | Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 μg/mL in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 μM for recombinant IDO. It is isolated from Penicillium and contains an epoxide group at C-19 and C-20, which is not present in benzomalvins A, B, or E. |
| CAS | 157047-98-8 |
| Formula | C24H17N3O3 |
| Molar Mass | 395.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jang, et al. Benzomalvin E, an indoleamine 2,3-dioxygenase inhibitor isolated from Penicillium sp. FN070315. J. Antibiot. (Tokyo) 65(4), 215-217 (2012). |
Benzomalvin C
CAS: 157047-98-8 F: C24H17N3O3 W: 395.41
Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.