Bcl-2-IN-2_product_DataBase

CAS: 2383085-86-5 F: C48H57N7O7S W: 876.07

Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM and also inhibits Bcl-xL with an IC50 of 4

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL[1].
Invitro	Bcl-2-IN-2 inhibits mutant Bcl-2-G101V with an IC50 of 1.2 nM. Bcl-2-IN-2 inhibits RS4;11 cellular proliferation with an IC50 of 1.9 nM[1].
Name	Bcl-2-IN-2
CAS	2383085-86-5
Formula	C48H57N7O7S
Molar Mass	876.07
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Yunhang GUO, et al. Bcl-2 INHIBITORS. WO2019210828A1.

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