| Bioactivity | BSF-466895(A-422885.66) is a Tie2 inhibitor with an IC50 of 5 nM and it can also inhibit Tie1[1][2]. |
| CAS | 262442-90-0 |
| Formula | C29H32Cl2FN7O2S |
| Molar Mass | 632.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jerry Adams, et al. A strategy for the design of multiplex inhibitors for kinase-mediated signalling in angiogenesis. Curr Opin Chem Biol. 2002 Aug;6(4):486-92. [2]. Dieter Marmé, et al. The impact of anti-angiogenic agents on cancer therapy. J Cancer Res Clin Oncol. 2003 Nov;129(11):607-20. |