| Bioactivity | BRD4-IN-5 (example 51) is a BRD4 inhibitor. The Ki values of the two BRD4 domains BDI_K57-E168 and BDII_E352-M457 are 9.7 nM and 16.1 nM, respectively. BRD4-IN-5 can be used in cancer research[1]. |
| Invitro | BRD4-IN-5 (example 51) 在人、小鼠、大鼠肝微粒体中的半衰期分别为 6 分钟，63 分钟和大于 120 分钟[1]。BRD4-IN-5 (3 天) 抑制乳腺癌细胞系 MX-1 增殖的 EC50 为 0.101 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> BRD4-IN-5 相关抗体: |
| CAS | 1445993-41-8 |
| Formula | C25H21F2N3O4 |
| Molar Mass | 465.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Le Wang, et al. Bromodomain inhibitors. International Publication Date. 2013.04.07. |
BRD4-IN-5
CAS: 1445993-41-8 F: C25H21F2N3O4 W: 465.45
BRD4-IN-5 (example 51) is a BRD4 inhibitor. The Ki values of the two BRD4 domains BDI_K57-E168 and BDII_E352-M457 are 9.
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