| Bioactivity | BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor. BMS-986308 is selective for ROMK over hERG. BMS-986308 can be used for heart failure research[1]. |
| In Vivo | BMS-986308（0.01-3 mg/kg；口服；一次）在容量负荷大鼠利尿模型中显示出疗效[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 2254333-97-4 |
| Formula | C24H25N7O2 |
| Molar Mass | 443.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jeremy M Richter, et al. Discovery of BMS-986308: A Renal Outer Medullary Potassium Channel Inhibitor for the Treatment of Heart Failure. J Med Chem. 2024 Jun 13;67(11):9731-9744. |
BMS-986308
CAS: 2254333-97-4 F: C24H25N7O2 W: 443.50
BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor. BMS-986308 is sele
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