| Bioactivity | BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, renal, bladder, and lung carcinoma. BMS 310705 induces significant apoptosis via mitochondrial-mediated pathway[1]. |
| Invitro | BMS 310705 (0.01-0.5 μM; 1 h) 诱导 OC-2 细胞凋亡[1]。BMS 310705 (-0.5 μM; 1 h) 增加 caspase-9/-3 的活性，并导致细胞色素 c 释放[1]。 Apoptosis Analysis[1] Cell Line: |
| Name | BMS 310705 |
| CAS | 280578-49-6 |
| Formula | C27H42N2O6S |
| Molar Mass | 522.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Uyar D, et al. Apoptotic pathways of epothilone BMS 310705. Gynecol Oncol. 2003 Oct;91(1):173-8. |
BMS 310705
CAS: 280578-49-6 F: C27H42N2O6S W: 522.70
BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, re
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