| Bioactivity | BIM-23027 is a selective agonist of sst2 receptor (EC50=0.32 nM), with similar effect to somatostatin (SRIF), a cyclic tetradecapeptide. BIM-23027 stimulates dopamine release, which is mediated by a Glu-dependent mechanism[1][2]. |
| Invitro | BIM-23027 (10,50 和 100 nM; 90分钟) 显著增加多巴胺水平[1]。BIM-23027 (50 nM; 100 nM SRIF 处理前 15 分钟孵育) 显著减弱了天然肽的作用[1]。BIM-23027 (30 nM; 30 分钟) 卡威酚刺激的基底鳞状细胞增加 60-70%，EC50 为 0.29 nM[2]。BIM-23027 与大鼠结肠粘膜 [125I]Tyr11-SRIF 结合位点的亚群相互作用[2]。 |
| Name | BIM-23027 |
| CAS | 78981-49-4 |
| Shortening | Cyclo[{(NMe)Ala}-FWKTF] |
| Formula | C43H54N8O7 |
| Molar Mass | 794.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
BIM-23027
CAS: 78981-49-4 F: C43H54N8O7 W: 794.94
BIM-23027 is a selective agonist of sst2 receptor (EC50=0.32 nM), with similar effect to somatostatin (SRIF), a cyclic t
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.