| Bioactivity | BI-6C9 is a highly specific BH3 interacting domain (Bid) inhibitor, which prevents mitochondrial outer membrane potential (MOMP) and mitochondrial fission, and protects the cells from mitochondrial apoptosis inducing factor (AIF) release and caspase-independent cell death in neurons[1]. | ||||||||||||
| Invitro | HT-22 cells shows reduction of cell viability around 4.5 h after Glutamate (3 mM and 5 mM) treatment. BI-6c9 (10 μM; 18 hours) significantly attenuates the loss of cell viability after Glutamate excitotoxicity[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | BI-6C9 | ||||||||||||
| CAS | 791835-21-7 | ||||||||||||
| Formula | C23H25N3O4S2 | ||||||||||||
| Molar Mass | 471.59 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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BI-6C9
CAS: 791835-21-7 F: C23H25N3O4S2 W: 471.59
BI-6C9 is a highly specific BH3 interacting domain (Bid) inhibitor, which prevents mitochondrial outer membrane potentia
Data collection：peptidedb@qq.com
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