| Bioactivity | BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1]. |
| Target | IC50: 40 nM (Aβ42) |
| Name | BI-1408 |
| CAS | 2231075-94-6 |
| Formula | C22H23FN6 |
| Molar Mass | 390.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gerlach K, et al. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators. Bioorg Med Chem. 2018 Jul 23;26(12):3227-3241. |