| Bioactivity | BAY-7081 is a potent, selective, orally active and soluble cyanopyridone-based PDE9A inhibitor with an IC50 of 15 nM[1]. |
| In Vivo | BAY-7081 (0.3 or 1.0 mg/kg; i.v. or p.o.) 表现出良好的体内药代动力学特性[1]。 Animal Model: |
| Name | BAY-7081 |
| Formula | C19H27ClN4O |
| Molar Mass | 362.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Meibom D, et al. BAY-7081: A Potent, Selective, and Orally Bioavailable Cyanopyridone-Based PDE9A Inhibitor. J Med Chem. 2022 Dec 22;65(24):16420-16431. |