Bioactivity | B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin[1]. |
Invitro | B746(1、3、10 μM;7 天)显著抑制分枝杆菌的生长[1]。 |
In Vivo | B746 降低米色小鼠脾脏中分枝杆菌的菌落形成单位 (CFU) 计数[1]。 |
Name | B 746 |
CAS | 103051-26-9 |
Formula | C26H20Cl2N4 |
Molar Mass | 459.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gangadharam PR, et al. In vitro, in vivo, and intracellular chemotherapeutic activity of B746, a clofazimine analogue against Mycobacterium avium complex. Tuber Lung Dis. 1992 Aug;73(4):192-9. |