Bioactivity | Avotaciclib hydrochloride is the hydrochloride form of Avotaciclib (HY-137432), a CDK1 inhibitor. Avotaciclib hydrochloride can be used for a few specific cancers, such as pancreatic cancer, in which CDK1 is abnormal and strongly expressed[1]. |
Target | CDK1 |
Name | Avotaciclib hydrochloride |
Formula | C13H12ClN7O |
Molar Mass | 317.73 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Reference | [1]. Xie Z, et al. Lessons Learned from Past Cyclin-Dependent Kinase Drug Discovery Efforts. J Med Chem. 2022 May 12;65(9):6356-6389. |