| Bioactivity | 4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetralithium is a potent P2Y2 and P2Y4 receptor agonist, with EC50s of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetralithium can be used in the study of crosslinking experiments, labeling of transcriptional complex[1][2]. |
| Name | 4-Thiouridine 5′-triphosphate tetralithium |
| CAS | 20188-72-1 |
| Formula | C9H11Li4N2O14P3S |
| Molar Mass | 523.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jacobson KA, et, al. Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors. Biochem Pharmacol. 2006 Feb 14;71(4):540-9. [2]. Bartholomew B, et, al. RNA contacts subunits IIo and IIc in HeLa RNA polymerase II transcription complexes. J Biol Chem. 1986 Oct 25;261(30):14226-31. |
4-Thiouridine 5′-triphosphate tetralithium
CAS: 20188-72-1 F: C9H11Li4N2O14P3S W: 523.94
4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetralithium is a potent P2Y2 and P2Y4 receptor agonist, with EC50s of 35 an
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