Bioactivity | Avacincaptad pegol (ARC1905) is is an anti-C5 RNA aptamer that inhibits the cleavage of complement factor 5 (C5) into C5a and C5b. Avacincaptad pegol is being used for the study of age-related macular degeneration (AMD). |
Name | Avacincaptad pegol sodium |
CAS | 1491144-00-3 |
Molar Mass | 53500.00 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Powers, J. P., Dairaghi, D. J., & Jaen, J. C. (2011). Advances in the Discovery of C5a Receptor Antagonists. Annual Reports in Medicinal Chemistry, 171–186. |