(R)-Pirtobrutinib_product_DataBase

CAS: 2101700-14-3 F: C22H21F4N5O3 W: 479.43

(R)-Pirtobrutinib ((R)-LOXO-305) is a less active enantiomer of Pirtobrutinib. Pirtobrutinib (LOXO-305), a highly select

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

(R)-Pirtobrutinib ((R)-LOXO-305) is a less active enantiomer of Pirtobrutinib. Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations[1].

Name

(R)-Pirtobrutinib

CAS

2101700-14-3

Formula

C22H21F4N5O3

Molar Mass

479.43

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Gomez E B , et al. Loxo-305, a Highly Selective and Non-Covalent Next Generation BTK Inhibitor, Inhibits Diverse BTK C481 Substitution Mutations[J]. Blood, 2019, 134(Supplement_1):4644-4644.

PeptideDB

(R)-Pirtobrutinib

CAS: 2101700-14-3 F: C22H21F4N5O3 W: 479.43