| Bioactivity | Autophagy-IN-2 (Compound 7h) is an autophagic flux inhibitor. Autophagy-IN-2 induces cancer cell apoptosis and can be used for triple-negative breast cancer research[1]. |
| Invitro | Autophagy-IN-2 (Compound 7h) (0-200 μM, 48 h) shows anti-viability activities against various cancer cells[1].Autophagy-IN-2 (0-20 μM, 0-48 h) suppresses autophagic flux and impairs DNA repair through down-regulating chromatin ubiquitination in a p62-dependent manner[1].Autophagy-IN-2 (0-20 μM, 48 h) induces cell cycle arrest at S-phase and mitochondria-dependent intrinsic apoptosis[1]. Cell Viability Assay[1] Cell Line: |
| Name | Autophagy-IN-2 |
| CAS | 2755454-90-9 |
| Formula | C17H19N5O |
| Molar Mass | 309.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Autophagy-IN-2
CAS: 2755454-90-9 F: C17H19N5O W: 309.37
Autophagy-IN-2 (Compound 7h) is an autophagic flux inhibitor. Autophagy-IN-2 induces cancer cell apoptosis and can be us
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.