| Bioactivity | Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. |
| Invitro | It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1]. |
| Name | Autocamtide-2-related inhibitory peptide |
| CAS | 167114-91-2 |
| Sequence | Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu |
| Shortening | KKALRRQEAVDAL |
| Formula | C64H116N22O19 |
| Molar Mass | 1497.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Autocamtide-2-related inhibitory peptide
CAS: 167114-91-2 F: C64H116N22O19 W: 1497.74
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
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