| Bioactivity | Artemisitene, a natural derivative of Artemisinin, is a Nrf2 activator with antioxidant and anticancer activities. Artemisitene activates Nrf2 by decreasing Nrf2 ubiquitination and increasing its stability[1][2]. | ||||||||||||
| Invitro | Artemisitene selectively induces DNA double-stranded breaks (DSBs) and apoptosis in various human cancer cells by suppressing the expression of topoisomerases in human cancer cells. Artemisitene selectively destabilizes c-Myc in human cancer cells by promoting the ubiquitination of c-Myc through the specific induction of the c-Myc E3 ligase NEDD4[2]. | ||||||||||||
| Name | Artemisitene | ||||||||||||
| CAS | 101020-89-7 | ||||||||||||
| Formula | C15H20O5 | ||||||||||||
| Molar Mass | 280.32 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Artemisitene
CAS: 101020-89-7 F: C15H20O5 W: 280.32
Artemisitene, a natural derivative of Artemisinin, is a Nrf2 activator with antioxidant and anticancer activities. Artem
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