| Bioactivity | Artemisiane E (Compound 8) is a potent PI3K/AKT pathway inhibitor with an IC50 of 8.9 μM[1]. |
| Target | IC50: 8.9 μM (PI3K/AKT pathway) |
| Invitro | Artemisiane E (Compound 8) (25 and 50 μM) inhibits AKT activity in MM121224 cells[1]. |
| Name | Artemisiane E |
| CAS | 2618700-77-7 |
| Formula | C20H22O5 |
| Molar Mass | 342.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dürr L, et al. A Dimerosesquiterpene and Sesquiterpene Lactones from Artemisia argyi Inhibiting Oncogenic PI3K/AKT Signaling in Melanoma Cells. J Nat Prod. 2022 Nov 25;85(11):2557-2569. |