Bioactivity | Aromadendrane-4β,10α-diol is a sesquiterpene alcohol. Aromadendrane-4β,10α-diol significantly ameliorates the Aβ1-42 peptide-induced memory impairment. Aromadendrane-4β,10α-diol can be used for Alzheimer's disease (AD) research[1]. |
In Vivo | Aromadendrane-4β,10α-diol(1 μg/小鼠,侧脑室注射)显着增加 Aβ1-42(400 pmol/小鼠,侧脑室注射)小鼠的抗氧化酶(谷胱甘肽,GSH)的活性并减少脂质过氧化[1]。 |
Name | Aromadendrane-4β,10α-diol |
CAS | 70051-38-6 |
Formula | C15H26O2 |
Molar Mass | 238.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Amoah SK, et al. Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer. Eur J Pharmacol. 2015 Dec 15;769:195-202. |